How VERQUVO® (vericiguat) May Help You Live Longer and Stay Out of the Hospital

VERQUVO may help you live longer and stay out of the hospital

VERQUVO is for adults with symptoms of chronic heart failure who have recently been hospitalized or received IV medicine, and have an ejection fraction of less than 45 percent.

A Heart Failure Hospitalization May Increase Your Chances of Going Back to the Hospital

Did you know?

A heart failure hospitalization may increase your chances of going back to the hospital.*

About 56% of patients hospitalized (or who receive IV medicine) due to increased heart failure symptoms return to the hospital within 30 days.*

*From a study of heart failure patients in the National PINNACLE Registry, where 1,851 patients with ejection fraction (amount of blood pumped with every heartbeat) less than or equal to 45% had increased symptoms of heart failure that required hospitalization or IV medicine.

See how VERQUVO works

VERQUVO® (vericiguat) May Help the Heart by Improving Blood Flow

VERQUVO may help the heart by improving blood flow

VERQUVO helps relax and widen the blood vessels in the heart. This makes it easier for the heart to pump more blood and oxygen throughout the body.

Make VERQUVO part of your daily routine

One Tablet

OnceDaily

WithFood

After you start taking VERQUVO, your doctor may change your dose to find the dose that's right for you. Be sure to tell your doctor about all the medicines you take.

Helpful Tip

If you are unable to swallow a VERQUVO tablet, crush the tablet and mix it with water right before taking it.

As directed by your doctor.

Helpful Tip

If you are unable to swallow a VERQUVO tablet, crush the tablet and mix it with water right before taking it.

Helpful Tip for VERQUVO® (vericiguat): If You Are Unable to Swallow a VERQUVO® (vericiguat) Tablet, Crush the Tablet and Mix it With Water Right Before Taking

As directed by your doctor.

Learn about the clinical trial

How Was VERQUVO® (vericiguat) Studied?

How was VERQUVO studied?

VERQUVO is the first and only FDA-approved medicine studied specifically in people who had a recent heart failure hospitalization or received IV medicine for their heart failure.

  • Over 5,000 people with heart failure participated

Patients had been hospitalized within the previous 6 months or had received IV medicine for heart failure within the previous 3 months.

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What is VERQUVO?

VERQUVO is a prescription medicine used in adults who are having symptoms of their chronic (long-lasting) heart failure, who have had a recent hospitalization or the need to receive intravenous (IV) medicines and have an ejection fraction (amount of blood pumped with each heartbeat) of less than 45 percent to reduce the risk of dying and to reduce the need to be hospitalized.

IMPORTANT SAFETY INFORMATION

VERQUVO may cause birth defects if taken during pregnancy.

  • Females must not be pregnant when they start taking VERQUVO.
  • For females who are able to get pregnant:

    - Your healthcare provider will do a pregnancy test to make sure that you are not pregnant before you start taking VERQUVO.

    - You must use effective forms of birth control during treatment and for 1 month after you stop treatment with VERQUVO. Talk to your healthcare provider about forms of birth control that you may use to prevent pregnancy during treatment.

    - Tell your healthcare provider right away if you become pregnant or think you are pregnant during treatment with VERQUVO.

Do not take VERQUVO if you:

  • are taking another medicine called a soluble guanylate cyclase stimulator (sGC). Ask your healthcare provider if you are not sure if you are taking an sGC medicine.
  • are pregnant.

Before taking VERQUVO, tell your healthcare provider about all your medical conditions, including if you:

  • are breastfeeding or plan to breastfeed. It is not known if VERQUVO passes into your breast milk. Do not breastfeed if you take VERQUVO. Talk with your healthcare provider about the best way to feed your baby if you take VERQUVO.

Tell your healthcare provider about all the medicines you take. Certain other medicines may affect how VERQUVO works.

The most common side effects of VERQUVO include:

  • low blood pressure
  • low red blood cells (anemia)

How should I take VERQUVO?

  • Take VERQUVO exactly as your healthcare provider tells you to.
  • Take VERQUVO 1 time each day with food.
  • Swallow VERQUVO tablets whole. If you are not able to swallow the tablet whole, you may crush VERQUVO tablets and mix with water right before taking your dose.
  • Your healthcare provider may change your dose — when you first start taking VERQUVO to find the best dose for you and how well you tolerate VERQUVO.
  • If you miss a dose, take the missed dose as soon as you remember on the same day of the missed dose. Do not take 2 doses of VERQUVO on the same day to make up for a missed dose.
  • If you take too much VERQUVO, call your healthcare provider or go to the nearest hospital emergency room right away.

You are encouraged to report negative side effects of prescription drugs to the FDA.

Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Please read the accompanying Medication Guide for VERQUVO, including the information about birth defects if taken during pregnancy, and discuss it with your doctor. The physician Prescribing Information also is available.